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Commonly in liquid form and available in various chemical compositions, solvents are substances that dissolve solutes to form solutions. The amount and type of solute that a solvent can dissolve is dependent upon temperature and polarity.
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Raspberry ketone glucoside is a melanogenesis inhibitor. It inhibits melanogenesis by activating the IL6/JAK1/STAT3 pathway, inhibiting the transcriptional activity of MITFa, and its downstream expression levels of the TYR and TYRP1a genes. It demonstrates significant whitening activity both in vitro (on B16F10 cells) and in vivo (in a zebrafish model).
Inhibits melanogenesis through the IL6/JAK1/STAT3 pathway.
Reduces transcriptional activity of MITFa and expression levels of TYR and TYRP1a genes.
Shows remarkable whitening activity on B16F10 cells in vitro.
Reduces internal melanin content and tyrosinase activity in a zebrafish model in vivo.
Up-regulates mRNA levels of GP130, IL6ST, JAK1, STAT3, and SOCS3b.
Activates macrophages in zebrafish embryos without affecting embryonic melanogenesis.
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Raspberry ketone glucoside is a melanogenesis inhibitor that activates the IL6/JAK1/STAT3 pathway, thereby inhibiting the transcriptional activity of MITFa and the downstream expression of TYR and TYRP1a genes. This compound demonstrates significant whitening activity in both B16F10 cells in vitro and in a zebrafish model in vivo.
Inhibits melanogenesis by activating the IL6/JAK1/STAT3 pathway
Inhibits transcriptional activity of MITFa
Reduces downstream expression of TYR and TYRP1a genes
Demonstrates whitening activity in B16F10 cells and zebrafish models
Appears as a white to off-white solid
Purity: 99.52%
Molecular formula: C16H22O7
Molecular weight: 326.34
Soluble in DMSO at 50 mg/mL with ultrasonication
Can be used as an analytical standard
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Raspberry ketone (Standard) is the analytical standard of Raspberry ketone, intended for research and analytical applications. It is a major aromatic compound of red raspberry, widely used as a fragrance in cosmetics and as a flavoring agent in foodstuff; it also shows PPAR-α agonistic activity.
The compound is the grade of analytical standard, which is the reference standard supplied assay.
It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
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(Z-LL)2 ketone is a ketone inhibitor with an IC50 value of 50 nM. It is designed for research use only and functions by inhibiting the processing of the p-Prl signal peptide.
Inhibits processing of the p-Prl signal peptide
Acts as a Ser/Thr protease inhibitor
Part of the metabolic enzyme/protease pathway
Has an IC50 value of 50 nM
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Perilla ketone is a naturally occurring xenobiotic compound. It is activated by pulmonary P450 cytochrome enzymes in the lung, which can lead to severe pulmonary damage and the development of diffuse pulmonary edema. It is for research use only.
Naturally occurring xenobiotic compound
Activated by pulmonary P450 cytochrome enzymes in the lung
Can lead to severe pulmonary damage and the development of diffuse pulmonary edema
For research use only
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Raspberry ketone (Standard) is the analytical standard of Raspberry ketone. It is a major aromatic compound of red raspberry, widely used as a fragrance in cosmetics and as a flavoring agent in foodstuff. It also exhibits PPAR-α agonistic activity. This product is intended for research and analytical applications.
Analytical standard for Raspberry ketone
Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
Purity: 99.95%
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Raspberry ketone (CAS 5471-51-2) is a small-molecule agonist targeting peroxisome proliferator-activated receptor alpha (PPAR- ) It is designed to activate PPAR- thereby influencing signaling pathways involved in lipid metabolism and energy homeostasis Raspberry ketone exerts its biological activity primarily through agonism of PPAR- Based on these pharmacological properties raspberry ketone holds research potential in the study of obesity and associated metabolic disorders
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Musk ketone is an artificial fragrance and a cytochrome P450 enzyme inducer. It exhibits mutagenic and comutagenic effects in Hep G2 cells and promotes neural stem cell proliferation and differentiation in cerebral ischemia by activating the PI3K/Akt signaling pathway. In the brain, musk ketone provides neuroprotection against stroke injury by inhibiting cell apoptosis.
Enhances proliferation and differentiation in neural stem cells (NSCs) with increased PI3K/Akt signaling pathway activation.
Inhibits cell viability of GC cells and prevents colony formation.
Induces cell cycle arrest and apoptosis in AGS and HGC-27 cells.
Ameliorates neurological deficit and reduces infarction and cerebral ischemic injury.
Increases CYP2B activity, protein, and mRNA levels, and boosts CYP1A enzyme activity.
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Raspberry ketone is a major aromatic compound of red raspberry, widely used as a fragrance in cosmetics and as a flavoring agent in foodstuff; it also shows PPAR-α agonistic activity.
Widely used as a fragrance in cosmetics and as a flavoring agent in foodstuff.
Shows PPAR-α agonistic activity.
Inhibits adipogenic and lipogenic gene expression in 3T3-L1 adipocytes.
Increases levels of total cholesterol, triglycerides, low-density lipoprotein cholesterol, and insulin-sensitive index in rats fed high-fat diets.
Decreases serum levels of AST, ALT, ALP, insulin resistance index, glucose, insulin, leptin, and TNF-α in rats with high-fat diet-induced NASH.
Causes increased SOD activities.
Exhibits cardioprotective action against isoproterenol-induced myocardial infarction in rats.
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